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Daily Life Physical Activity, Quality of Life and Symptoms of Depression and Anxiety in Adult Patients with Type 2 Diabetes: A Preliminary Study  [PDF]
Ioannis D. Morres, Evlalia Touloudi, Antonis Hatzigeorgiadis, Athanasios Z. Jamurtas, Odysseas Androutsos, Yannis Theodorakis
Psychology (PSYCH) , 2021, DOI: 10.4236/psych.2021.128080
Abstract: Purpose: Many diabetic patients experience depression/anxiety and poor Quality of Life (QoL). Daily life Physical Activity (PA) is linked to improved depression/anxiety and QoL across various patients, but relevant studies in diabetic patients are scarce. This preliminary study examined if daily life PA is linked to better depression/anxiety and QoL in patients with Type 2 Diabetes (T2D). Methods: A total of 51 adult T2D outpatients (Mean age = 63.31 years; Standard Deviation = 13.88) completed questionnaires for PA, QoL and depression/anxiety. Descriptive and correlation statistics were computed for all variables of interest. Hierarchical regression analysis examined if days of PA at light, moderate or vigorous intensity predict improved depression/anxiety and QoL. Results: The sample was insufficiently active; also, 32% showed poor QoL, and 22% and 30%, respectively, had at least moderate depression or anxiety symptoms. Days of PA at light and moderate but not at vigorous intensity demonstrated small-to-moderate inverse correlations with improved depression/anxiety and QoL. Hierarchical regression analyses demonstrated that, after controlling for age and body mass index, days of PA at light and moderate intensities predicted lower depression and explained 39% of the variance, whereas only days of PA at light intensity predicted lower anxiety and better QoL, explaining, respectively, 30% and 40% of the variance. Discussion: This preliminary study for adults with T2D found that days of light and moderate intensity PA were linked to improved depression, but days of only light intensity PA were linked to improved anxiety and QoL. Findings are encouraging, especially since our sample was insufficiently active. However, larger samples with T2D adults are needed for firmer conclusions.
The Effects of an Olive Fruit Polyphenol-Enriched Yogurt on Body Composition, Blood Redox Status, Physiological and Metabolic Parameters and Yogurt Microflora
Anastasios Mpesios,Athanasios Z. Jamurtas,Chrysanthi Mitsagga,Demetrios Kouretas,Ioannis Giavasis,Kalliopi Georgakouli,Konstantinos Petrotos
- , 2016, DOI: 10.3390/nu8060344
Abstract: In the present study we investigated the effects of an olive polyphenol-enriched yogurt on yogurt microflora, as well as hematological, physiological and metabolic parameters, blood redox status and body composition. In a randomized double-blind, crossover design, 16 (6 men, 10 women) nonsmoking volunteers with non-declared pathology consumed either 400 g of olive fruit polyphenol-enriched yogurt with 50 mg of encapsulated olive polyphenols (experimental condition—EC) or 400 g of plain yogurt (control condition—CC) every day for two weeks. Physiological measurements and blood collection were performed before and after two weeks of each condition. The results showed that body weight, body mass index, hip circumference and systolic blood pressure decreased significantly (p < 0.05) following the two-week consumption of yogurt regardless of condition. A tendency towards significance for decreased levels of low density lipoprotein (LDL) cholesterol (p = 0.06) and thiobarbituric acid reactive substances (p < 0.05) following two weeks of polyphenol-enriched yogurt consumption was observed. The population of lactic acid bacteria (LAB) and production of lactate in yogurt were significantly enhanced after addition of olive polyphenols, contrary to the population of yeasts and molds. The results indicate that consumption of the polyphenol-enriched yogurt may help individuals with non-declared pathology reduce body weight, blood pressure, LDL cholesterol levels and lipid peroxidation, and promote growth of beneficial LAB
The First Blood Collection Attempt for Doping Control in an Olympic Tournament: Data on the Procedure Applied in Athens 2004 Olympic Games
Christina Tsitsimpikou, Athanasios Z. Jamurtas, Athanasios Tsiokanos, Ioannis G. Fatouros, Konstantinos Tsarouhas2, Eva Karachaliou, Patrick Schamasch and Dimitris Valasiadis
The Open Forensic Science Journal , 2008, DOI: 10.2174/1874402800801010027]
Abstract: The procedure for blood sampling in doping control, implemented for the first time as part of the official forensic testing programme in the Athens 2004 Summer Olympic Games is described. 743 whole blood and serum samples from 37 sports were analyzed. In serum human growth hormone and hemoglobin based oxygen carriers were screened for. In whole blood samples heterologous blood transfusion was detected. Routine haematological parameters (hematocrit, haemoglobin) were followed in a very limited range only in Modern Pentathlon under the responsibility of the respective International Federation. The majority of the blood samples collected concerned events in athletics. Endurance sports accounted for 81% of the whole blood sampling. Athletics, swimming and rowing represented 55% of the serum samples analyzed. Extension of testing for oxygen transport enhancing agents in anaerobic sports should be seriously considered by future organizers and the International Olympic Committee. The mean time for an athlete to report to the Doping Control Station for blood collection was 6.1 hours; 27% of the athletes tested (from 19 sports) failed to appear within the 12-hours time limit set. Training of the phlebotomists was proven effective. Only 25 athletes of those tested (3%) reported to have felt uncomfortable. The majority of complaints (47%) concerned the prolonged waiting period and the long blood collection time (48%). Finally, an earlier agreement between all involved parties, attempts to decrease the time to appear at the site of blood collection and shortening of the duration of blood collection and sealing of the samples are recommended.
Iron Supplementation Effects on Redox Status following Aseptic Skeletal Muscle Trauma in Adults and Children
Alexandra Avloniti,Athanasios Tsiokanos,Athanasios Z. Jamurtas,Athanasios Zalavras,Chariklia K. Deli,Ioannis G. Fatouros,Kalliopi Georgakouli,Vassilis Paschalis,Yiannis Koutedakis
- , 2017, DOI: 10.1155/2017/4120421
Abstract:
The effects of low and high glycemic index foods on exercise performance and beta-endorphin responses
Athanasios Z Jamurtas, Trifon Tofas, Ioannis Fatouros, Michalis G Nikolaidis, Vassilis Paschalis, Christina Yfanti, Stefanos Raptis, Yiannis Koutedakis
Journal of the International Society of Sports Nutrition , 2011, DOI: 10.1186/1550-2783-8-15
Abstract: Carbohydrate ingestion prior to exercise has been shown to affect metabolic responses and performance [1]. It is suggested that carbohydrate feeding prior to exercise provides additional supplies for oxidation, results in increased muscle glucose uptake and reduced liver glucose output during exercise [2] and the enhanced blood glucose availability may preserve muscle glycogen stores [3].β-endorphin is one of the peptides that has been suggested to play a role in glucose metabolism at rest [4,5] and during exercise [6-9]. β-endorphin is an opioid peptide representing the C-terminal 31 amino acid residue fragment of pro-opiomelanocortin. Data indicates that stress is a potent inducer of β-endorphin release and it is well known that exercise of sufficient intensity and duration elevates its circulating concentrations [10-13]. The fact that both central and peripheral β-endorphin levels appear to change under hyperglycemic or hypoglycemic conditions suggests that endorphins are implicated in the regulation of glucose homeostasis [4,13]. Specifically, β-endorphin infusion attenuated glucose decline during prolonged exercise [6,7,9,14,15], a result that was accompanied by marked changes in glucoregulatory hormones such as insulin and glucagon whereas opiate blockade produced opposite results [6,14,15]. Thus, there is enough data to support that β-endorphin could be affected by differences in blood glucose availability as the ones produced by the consumption of different glycemic index (GI) foods.Glycemic index ranks foods according to their effect on blood glucose levels compared to a reference food [16]. There are several studies that examined the effects of foods of various GI values prior to exercise with inconsistent results being reported in regards to performance [17-20] and carbohydrate utilization during exercise [17,19]. Exercise performance has been positively affected by low glycemic index (LGI) food [17] and remained unaffected by high glycemic index (HGI) fo
Exercise in Glucose-6-Phosphate Dehydrogenase Deficiency: Harmful or Harmless? A Narrative Review
Athanasios Z. Jamurtas,Chariklia K. Deli,Dimitrios Draganidis,Ioannis G. Fatouros,Kalliopi Georgakouli,Konstantinos Papanikolaou,Panagiotis Tsimeas
- , 2019, DOI: 10.1155/2019/8060193
Abstract:
Exercise-Induced Reductive Stress Is a Protective Mechanism against Oxidative Stress in Peripheral Blood Mononuclear Cells
Alexandros Priftis,Aristidis S. Veskoukis,Athanasios Z. Jamurtas,Chariklia K. Deli,Christina Papanikolaou,Demetrios Kouretas,Dimitrios Stagos,Ypatios Spanidis
- , 2018, DOI: 10.1155/2018/3053704
Abstract:
The redox-dependent regulation of satellite cells following aseptic muscle trauma (SpEED): study protocol for a randomized controlled trial
Alexios Batrakoulis,Athanasios Chatzinikolaou,Athanasios Z. Jamurtas,Chariklia K. Deli,Dimitrios Draganidis,Ioannis G. Fatouros,Kalliopi Georgakouli,Konstantinos Papanikolaou,Panagiotis Tsimeas,Vassiliki C. Laschou
- , 2019, DOI: 10.1186/s13063-019-3557-3
Abstract:
Respiratory and Immune Response to Maximal Physical Exertion following Exposure to Secondhand Smoke in Healthy Adults
Andreas D. Flouris, Giorgos S. Metsios, Andres E. Carrill, Athanasios Z. Jamurtas, Polychronis D. Stivaktakis, Manolis N. Tzatzarakis, Aristidis M. Tsatsakis, Yiannis Koutedakis
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0031880
Abstract: We assessed the cardiorespiratory and immune response to physical exertion following secondhand smoke (SHS) exposure through a randomized crossover experiment. Data were obtained from 16 (8 women) non-smoking adults during and following a maximal oxygen uptake cycling protocol administered at baseline and at 0-, 1-, and 3- hours following 1-hour of SHS set at bar/restaurant carbon monoxide levels. We found that SHS was associated with a 12% decrease in maximum power output, an 8.2% reduction in maximal oxygen consumption, a 6% increase in perceived exertion, and a 6.7% decrease in time to exhaustion (P<0.05). Moreover, at 0-hours almost all respiratory and immune variables measured were adversely affected (P<0.05). For instance, FEV1 values at 0-hours dropped by 17.4%, while TNF-α increased by 90.1% (P<0.05). At 3-hours mean values of cotinine, perceived exertion and recovery systolic blood pressure in both sexes, IL4, TNF-α and IFN-γ in men, as well as FEV1/FVC, percent predicted FEV1, respiratory rate, and tidal volume in women remained different compared to baseline (P<0.05). It is concluded that a 1-hour of SHS at bar/restaurant levels adversely affects the cardiorespiratory and immune response to maximal physical exertion in healthy nonsmokers for at least three hours following SHS.
Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study
Antonios Stavropoulos-Kalinoglou, Giorgos S Metsios, Vasileios F Panoulas, Karen MJ Douglas, Alan M Nevill, Athanasios Z Jamurtas, Marina Kita, Yiannis Koutedakis, George D Kitas
Arthritis Research & Therapy , 2008, DOI: 10.1186/ar2429
Abstract: A total of 392 patients (290 females) with RA were assessed for body mass index (BMI), body fat (BF), fat-free mass (FFM), and waist circumference. Erythrocyte sedimentation rate, C-reactive protein, Disease Activity Score-28, and Health Assessment Questionnaire score were used to assess disease activity and severity. Smoking habit (current smoker, ex-smoker, or never-smoker) and intensity (pack-years) were also noted.Current smokers had a significantly lower BMI compared with ex-smokers (mean difference: male -2.6, 95% confidence interval [CI]: -3.5 to -1.7; female: -2.6, 95% CI: -4.8 to -0.5) and never-smokers (mean difference: male -1.8, 95% CI: -3 to -0.6; female: -1.4, 95% CI: -2.4 to -0.4). Similarly, the BF of current smokers was lower compared with that of ex-smokers (mean difference: male: -4.3, 95% CI: -7.5 to -1.2; female: -3.4, 95% CI: -6.4 to -0.4) and never-smokers (mean difference: male: -3.3, 95% CI: -6.3 to -0.4; female: -2.1, 95% CI: -4 to -0.2). FFM did not differ between groups. Finally, current smokers had a significantly smaller waist circumference compared with ex-smokers only (mean difference: male: -6.2, 95% CI: -10.4 to -1.9; female: -7.8, 95% CI: -13.5 to -2.1). Following adjustments for age, disease duration, and HAQ score, smoking remained a significant predictor for BMI (P < 0.001), BF (P < 0.05), and waist circumference (P < 0.05). Pack-years were inversely correlated with BF (r = -0.46; P < 0.001), and heavy smokers exhibited a significantly lower FFM (P < 0.05) compared with all other participants.Within the limitations of a cross-sectional study, it appears that cigarette smoking associates with reduced BMI and BF in patients with RA and heavy smoking associates with lower muscle mass. Smoking cessation appears to associate with increased BMI, BF, and waist circumference in these patients. These results should be confirmed in prospective studies. Given the numerous adverse effects of smoking on general health and RA, patients should
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